The OncologyTranslational Science (OTS) External Network Leader role will drive externalcollaborations, partner with Business Development and Licensing (BD&L),manage people from the collaborations, and have Cancer Research as well asCancer Immunology background. This OTS Leader will not work on internalprojects but will be a scientific strategy champion for oncology research viaexternal collaborations, maintaining BI at the forefront of scientific andtechnological advances in oncology biomarker research with external networksand visibility. This Leader will need strong influencing and networking skillsand will identify and evaluate external innovation opportunities forexploratory patient selection biomarkers, as well as pharmacodynamic biomarkersfor demonstration of MoA-associated biological effects with focus on noveltherapeutic concepts, emerging technologies and new therapeutic modalities.Furthermore, this leader will foster reverse translation (bedside-to-benchtranslation), via developing potential biomarkers in partnership withacademic/medical centers with comprehensive translational capabilities enabledthrough innovative patient-centric disease modeling, pre-clinical trialplatforms, and proprietary technologies to systematically inform on tumorresponse and resistance.
Therefore, thisindividual will scout for high quality external translational biomarker scienceactivities and, in a matrix structure, coordinate them with the internalactivities in Ridgefield USA and in Vienna Austria, as well as with otheroncology research sites with the ultimate goal of developing immunecell-directed and tumor cell-directed cancer therapies.
The integration ofinternal and external biomarker research activities will drive biomarker-basedpreclinical understanding of MoA with the ultimate goals to drive subsequentearly clinical evaluation and support biomarker based proof of clinicalprinciple (PoCP), in close collaboration with the other disciplines in DR,BD&L, Translational Medicine and Clinical Pharmacology (TMCP), TA Medicineand Computational Science.
This leader will also bea BI representative for implementation of international research collaborationswith academic and/or biotech partners.
As an employee ofBoehringer Ingelheim, you will actively contribute to the discovery,development and delivery of our products to our patients and customers. Ourglobal presence provides opportunity for all employees to collaborateinternationally, offering visibility and opportunity to directly contribute tothe companies' success. We realize that our strength and competitive advantagelie with our people. We support our employees in a number of ways to foster ahealthy working environment, meaningful work, diversity and inclusion,mobility, networking and work-life balance. Our competitive compensation andbenefit programs reflect Boehringer Ingelheim's high regard for our employees.
- Identify andevaluate external collaborations and partnerships (academic and medical centersand CROs in collaboration with BD&L) for development of biomarkerstrategies for Oncology projects, starting at the Discovery Research stage,with a primary focus on timely execution of translational activities andgeneration of evidence to support early clinical development, clinicalmeasurements of PoPP (proof of pharmacological principle) and PoCP (proof ofclinical principle) studies in patients.
- Implement and overseeexternal collaborations with academia and CROs with expertise in translationalcancer immunology and cancer cell targeted therapies, and cutting edgetechnologies with the aim to develop genomic, biochemical, immunological,imaging and cellular technologies and associated biomarkers, intranslationally-relevant settings, including using pre-clinical disease modelsrelevant to cancer to evaluate PD biomarkers, and enable development andtesting of patient selection strategies.
- Function as aninternal expert in immune-oncology and cancer cell directed biomarkers. Followscientific trends in the area of biomarkers and their utilization as PD markersand companion diagnostics in the field of oncology
- Build and maintain adeep network of external connections in oncology translational science and
- present and reportdata in external meetings and publications.
- Contribute to thedevelopment of others outside of formal reporting lines by creating andproviding opportunities for project responsibilities and matrix leadership inexternal collaborations.
- Coordinateeffectively with internal OTS activities, research teams and disciplines acrossthe global Discovery Research Organization and with the Biomarker Leadershipdisciplines (TMCP and TA Oncology Medicine) at both local and global level tocoordinate the execution of the Oncology Translational Strategy.
- Perform all companybusiness in accordance with all company policies and procedures. Demonstratehigh ethical and professional standards with all business contacts in order tomaintain excellent reputation within the medical and pharmaceutical community.
- PhD, MD, or MD/PhDfrom an accredited institution in immunology, oncology, or related field.
- Extensive trackrecord of impactful publications.
- Minimum of five (5)years of professional experience in cancer research in an academic and/orbiopharmaceutical setting.
- Extensive expertisein translational research in oncology, ideally including immune-oncology andcancer cell directed concepts; demonstrated success in translating biomarkerstrategies to enable development of small and large molecule clinicalcandidates preferred.
- Must have a broadunderstanding of drug discovery and development, strong scientific expertiseand external network, and be able to influence others to understand andimplement innovative scientific biomarker approaches.
- Excellentcommunication capabilities, collaborative behaviors, and motivational skillswith demonstrated ability to work with/ lead multi-disciplinary teams based onteam science criteria.
- Exceptionalknowledge in cancer biomarker research, with a strong publication track-record,external network and visibility.
- Experience indevelopment of biomarkers, novel assay development and data interpretation ofbiomarkers between human cancer and mouse tumor models with exceptionalknowledge in the discovery, development and utilization of biomarkers andbiomarker-technologies.
- Demonstrated abilityto influence; experience with cross-functional teams.
- Good knowledge ofnovel clinical translational approaches including technologies, enablingclinical biomarker identification and validation
- Experience in aglobal organization and matrix environment would be an advantage.
- Must have expertcommunication and stakeholder management skills.
- Must be legallyauthorized to work in the United States without restriction.
- Must be willing totake a drug test and post-offer physical (if required)
- Must be 18 years ofage or older
Who We Are:
At Boehringer Ingelheim we create value through innovationwith one clear goal: to improve the lives of patients. We develop breakthroughtherapies and innovative healthcare solutions in areas of unmet medical needfor both humans and animals. As a family owned company we focus on long termperformance. We are powered by 50.000 employees globally who nurture adiverse, collaborative and inclusive culture. Learning and development forall employees is key because your growth is our growth.
Want to learn more? Visitboehringer-ingelheim.com andjoin us in our effort to make more health.
BoehringerIngelheim, including Boehringer Ingelheim Pharmaceuticals, Inc., BoehringerIngelheim USA, Boehringer Ingelheim Animal Health USA Inc., BoehringerIngelheim Animal Health Puerto Rico LLC and Boehringer Ingelheim Fremont,Inc. is an equal opportunity and affirmative action employer committed toa culturally diverse workforce. All qualified applicants will receiveconsideration for employment without regard to race; color; creed; religion;national origin; age; ancestry; citizenship status, marital, domesticpartnership or civil union status; gender, gender identity or expression;affectional or sexual orientation; pregnancy, childbirth or related medicalcondition; physical or psychiatric disability; veteran or military status;domestic violence victim status; genetic information (including the refusal tosubmit to genetic testing) or any other characteristic protected by applicablefederal, state or local law.