Research Associate I/II � Human Cell Types
We are seeking an experienced Research Associate I/II to participate in experiments designed to reveal the cellular complexity of the human brain. This individual will join the Human Cell Types group at the Allen Institute for Brain Science to support key tasks in generating and analyzing multiplexed FISH data in organotypic slices. This individual will also support the generation and characterization of viral reporter vectors as well as gene therapy vectors. Experience with confocal fluorescence microscopy, coding with R or Python, molecular biology, and a basic understanding of neuroscience is desired. Ultimately, this individual should enjoy working as a part of a team to conduct ground-breaking research that aims to understand human brain function and address human neurological diseases.
The ideal Research Associate I/II candidate would have experience with imaging and molecular biology to conduct multiplexed FISH experiments that support multiple major objectives at the Allen Institute for Brain Science. In this role, the primary responsibilities include: receiving, staining, imaging and analyzing human and NHP brain organotypic slice cultures to reveal the molecular nature of distinct cell types and connect them to brain structure and function. Secondary responsibilities will involve supporting molecular biology efforts to generate reporter vectors and therapeutic vectors. This position requires a strong interest in human neurobiology, and the desire to work in a fast-paced team environment on large scientific projects.
- Receive and archive organotypic slice cultures
- Multiplexed FISH experimentation, imaging and data analysis
- Maintaining experimental and analysis consistency across time
- Identify and report any data quality issues
- Presentation of results to group
- Must follow good laboratory practices?
- BA/BS biological science or related field.
- RA I: 0-2 years of experience in a laboratory or research environment
- RA II: 2-4 years of experience in a laboratory or research environment
- MS in a biological science or related field. Neuroscience knowledge preferred.
- Experience conducting immunostaining or FISH experiments.
- Experience in designing, executing, and trouble-shooting molecular biology tasks.
- Experience working in a timeline, milestone-driven, and team work environment is beneficial.
- Excellent organizational skills
- Proficiency in MS Office programs, Molecular Biology software, and experience with R and Python preferred
It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.