We are seeking a chemist to join the High Throughput Screening (HTS) Group within Chemical Research and Development (CRD) in Groton. CRD, as part of Worldwide R&D in Pharmaceutical Sciences, is responsible for the development of process technology for the production of active pharmaceutical ingredients (API). HTS scientists within CRD utilize automation and technology to speed development, enable rapid adoption of new chemistry, and assist in identifying the commercial synthetic route. CRD HTS scientists partner with chemistry specialists in other disciplines, including analytical, data management, engineering, and discovery chemistry to support the development teams they serve.
The successful candidate will enable and develop processes to pharmaceutical drug candidates through automation, HTS, and technology in a laboratory setting. The ability to work on and lead multi-disciplinary teams involving chemists, analysts, engineers, and technologists, and to represent CRD on cross-functional teams is essential.
- The successful candidate will work in the HTS laboratory and assist in a number of screening workflow platforms within a dynamic, team-oriented environment and lead in the development of new technologies.
- The successful candidate would identify opportunities to improve or propose new synthetic routes for the preparation of API’s. This position requires laboratory experimentation, participation on API project teams and work in collaboration with scientists from Analytical R&D and other disciplines such as engineering to further develop synthetic processes.
- Interpretation of analytical data to drive synthetic experimental plans and ability to utilize electronic tools (electronic notebook, HTS and automation software) to gather and document information.
- The successful candidate would also be willing to learn and apply new technology, such as automation and coding, to process development challenges and contribute to explore improvements.
- Compliance on safety and regulatory requirements is expected and documented through our internal training program.
- The successful candidate would also participate in key initiatives for HTS and contribute to continuous improvement work in the department and advancement of the HTS discipline through technology, workflow or business impact.
- PhD. in Organic Chemistry, Chemical Engineering, or related discipline with 0-3 years relevant experience or MS in Organic Chemistry, Chemical Engineering, or related discipline with 3-6 years of relevant experience.
- State of the art knowledge of synthetic methodology, including aspects of asymmetric synthesis, green chemistry, catalysis and physical organic chemistry as it relates to reaction mechanism is expected. The ability to employ analytical tools, computational and statistical methodology, and automated laboratory technologies to enhance process development efficiency is desirable. Experience with flow chemistry or similar technology would be beneficial.
- Excellent written and oral communication skills, the ability to effectively influence the work of others and a general knowledge of drug development and the pharmaceutical industry are key.
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- This job is Pfizer (Exempt US Grade: 9
- Eligible for Relocation Package Yes
- US/PR colleagues who are issued an Incident Final Warning (IFW) disciplinary action are not eligible to post and compete for a position for a period of 12-months from the date an IFW is issued.
N (Other) (United States of America)
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